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Ativan (Lorazepam)

Ativan is anti-anxiety agent used to treat panic attacks, neurosis-like states, and various disorders caused by stress. Brand name for lorazepam is Ativan.

Pharmacological effect

The active substance of Ativan- lorazepam 5 mg has a central muscle relaxant, hypnotic, anxiolytic, sedative, anticonvulsant and anti-emetic effect. Ativan 1 mg relates to means of the average duration that is used to treat panic attacks and to reduce anxiety. According to instruction lorazepam generic is not effective in acute delusional, hallucinatory, affective disorders, and in the treatment of psychotic disorders such as depression or anxiety associated with it, it is not recommended as the primary drug. Long-term use of generic Ativan can result in tolerance and gradual decrease of efficiency as well as to the development of drug dependence and addiction.

Indications for use of Ativan 5mg

According Ativan instructions lorazepam pill should be used during:

  • Sleep disorders, which are caused by anxiety or short-term stressful situation;
  • Epilepsy and epileptic status, often in combination therapy; Psych-reaction states and phobias;
  • Emotional reactivity states;
  • Psychosomatic disorders and headaches for respiratory, gastrointestinal, cardiovascular and other diseases of the internal organs;
  • Endogenous psychoses including manic and catatonic state, and states of anxiety and excitement in schizophrenia;
  • Panic disorder;
  • Acute alcoholic delirium;
  • Neuroses and neurosis-like states;
  • Symptomatic convulsive states.

Contraindications of 5 mg lorazepam

Contraindications to Ativan application according to the instructions are as follows:

  • Angle-closure glaucoma;
  • Myasthenia gravis;
  • Acute alcohol intoxication;
  • Acute intoxication with psychotropic drugs.

Hypersensitivity to Ativan 5 mg or other components of the preparation.

Ativan in any dosage forms should not be used during pregnancy, especially during the first trimester and during breastfeeding. The drug is administered in tablet since 12 years, as a solution for injection – since 18 years old.

In addition, ativan tablet should be used with caution in:

  • Suspicion of angle-closure glaucoma and sleep apnea;
  • Epilepsy;
  • Porphyry;
  • Impaired renal function;
  • Hyperkinesia;
  • Psychoses;
  • Choquet;
  • Organic diseases of the brain;
  • Coma;
  • Severe depression;
  • Severe chronic obstructive pulmonary disease;
  • Hypoproteinemia.

How to use lorazepam tablets

Adults usually take a daily dose of lorazepam 2mg high, divided into 3 doses. And the half of the daily dose is recommended to take in the morning and in the afternoon, and the second half - just before bedtime.

Depending on the symptoms, the dosage of Ativan may vary in neurological practice - 1 mg to 3 times a day. For arresting excitation it is apply 2 mg of Ativan by intravenous injection. The maximum daily dose for ingestion is 10 mg for intramuscular and intravenous administration a single dose should not exceed 4mg lorazepam. A sharp lifting of Ativan may develop the withdrawal symptoms. Caution must be exercised with concomitant use of Ativan with means, which have a depressing effect on the central nervous system, and with the ethanol-containing drugs, because the combination of drugs can lead to aggression, psychomotor agitation and pathological intoxication. It should also be borne in mind that nicotine reduces the activity of Ativan.

Side effects of Ativan

According the instruction ativan 10mg rarely has side effects and by the judging of the reviews, the drug therapy is generally well tolerated. The most common side effects include disorders: Central nervous system as fatigue, muscular weakness, ataxia, vertigo, amnesia; The digestive system: constipation, dry mouth, nausea, appetite disorders and hepatic function, dysphagia, diarrhea.

Also use of Ativan can lead to changes in patterns of peripheral blood and cause minor allergic reactions such as itching and skin rash.

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