Archive for July, 2010

Drugs Used in Prevention of Migraine

There are several drugs that can be used for prophylaxis of migraine headache. Some of the drugs which have efficacy as a preventive agent for migraine but have considerable side effects and are not commonly used. Many of the drugs with efficacy as preventive agent in migraine are not approved by the FDA and some are approved by FDA for prophylaxis of migraine (local rules should always be sought before prescribing a drug for prophylaxis of migraine). Some drugs are not available in some countries and availability is an important factor.

FDA has approved propranolol, timolol, sodium valproate, and topiramate for prophylactic treatment of migraine. Methysergide is also approved by FDA for prophylaxis of migraine, but not available in the United States. There are also many more drugs which shows efficacy in prevention of migraine but not approved by FDA for prophylaxis of migraine.

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